S protein model image

A model of an S-protein. Illustration: Dr. Yeolkyo Choi/Lehigh

Wonpil Im Featured in Wired Italia

The bioengineering professor discusses his work on the first open source model of the coronavirus spike protein.

Story by

Emily Collins

Tags

Wired Italia featured Wonpil Im, professor of bioengineering, in the article "Coronavirus, the first complete and open source model of the spike protein arrives."

The virus SARS coronavirus 2 (SARS-CoV-2) is the known cause of coronavirus (COVID-19). The “spike” or S protein facilitates viral entry into host cells. Researchers from Lehigh University, Seoul National University in South Korea and the University of Cambridge in the UK have produced open source models of the spike protein that contain all the components and atoms of this protein. The researchers say this is of particular importance because the S protein plays a central role in viral entry into cells, making it a main target for vaccine and antiviral drug development.

"Our work provides the first models, available to all scientists, of the entire spike protein of the fully glycosylated Sars-Cov-2 virus," said Im.

Scientists can use the models to conduct innovative and novel simulation research for the prevention and treatment of COVID-19, according to Im.

The full article can be read on the Wired Italia website.

Story by

Emily Collins

Tags

Related Stories

covid illustration

Scientists Identify Virus-Cell Interaction That May Explain COVID-19’s High Infection Rate

Lehigh researchers quantify the interaction between the spike protein of SARS-CoV-2—the virus that causes COVID-19—with the ACE2 receptors in human cells.

Claudio-Ventrella

Immunotherapy for Deadly Bacteria Shows Early Promise

Researchers design a compound that triggers an immunological response to Gram-negative bacteria.

Lehigh_Univeristy_Research_Review_Bacteria_Main

CHARMM-GUI Provides a Close-up Look at Bacteria

Wonpil Im’s web-based graphical user interface, CHARMM GUI, eases modeling of complex biomolecular systems, possibly paving the way for better understanding of drug-resistant bacteria.